Guillaume St-Jean, DMV, PhD, DACVP
Associate professor, Faculty of veterinary medicine, University of Montreal
Our primary field of interest is the roles played by signaling pathways in the development and function of the uterus and pathogenesis of uterine diseases in human and animals. The uterus is a dynamic organ. Its development and function are carefully coordinated by numerous signaling pathways expressed during embryogenesis and adult life. TGF-b and Hippo are counted amongst these pathways. They also contribute to the development of numerous diseases. Using functional genomics and comparative pathology approaches, we study the roles of some of these pathways in the pathogenesis of uterine diseases. Our current research study the roles of Hippo signaling in the uterine function and development of endometritis in cows.